Fullmetal Alchemist

Fullmetal Alchemist follows brothers Edward and Alphonse Elric in a world where alchemy is a science, as they search for the mythical Philosopher's Stone to restore their bodies after a failed attempt at human transmutation cost Edward limbs and Alphonse his entire body. The brothers' quest involves them becoming State Alchemists and uncovering a conspiracy tied to the stone, forcing them to question the value of human life and their own morals along the way